Exhibit 15.4

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May 13, 2025

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Securities and Exchange Commission

100 F Street, N.E.

Washington, DC 20549

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Commissioners:

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We have read the statements made by Santech Holdings Ltd under Item 16F of its Form 20-F dated May 13, 2025. We agree with the statements concerning our Firm in such Form 20-F; we are not in a position to agree or disagree with other statements of Santech Holdings Ltd contained therein.

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Very truly yours,

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/s/ Marcum Asia CPAs LLP

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Marcum Asia CPAs LLP