Exhibit 16.1

 

September 26, 2025

Securities and Exchange Commission

100 F Street, N.E.

Washington, DC 20549

Commissioners:

We have read the statements made by Semnur Pharmaceuticals, Inc. (formerly known as Denali Capital Acquisition Corp.) under Item 4.01 of its Form 8-K dated September 26, 2025. We agree with the statements concerning our Firm in such Form 8-K; we are not in a position to agree or disagree with other statements of Semnur Pharmaceuticals, Inc. contained therein.

 

Very truly yours,

/s/ Marcum Asia CPAs LLP

Marcum Asia CPAs LLP

NEW YORK OFFICE • 7 Penn Plaza • Suite 830 • New York, New York • 10001

Phone 646.442.4845 • Fax 646.349.5200 • www.marcumasia.com